A 23-year-old woman presented with a I-day history of a severe migrain
elike headache with a normal neurological examination. The headache re
solved after a ketorolac injection, but recurred a few hours later. An
MRI scan of the brain showed a hemorrhagic pituitary macroadenoma for
which she underwent transsphenoidal removal of the tumor 1 month late
r. Although uncommon, pituitary hemorrhage with and without apoplexy s
hould be considered in the differential diagnosis of acute headache. P
ituitary hemorrhage can be routinely identified on an MRI scan even wi
thout pituitary views. However, the pathology can be overlooked and un
derimaged on a CT scan for acute headache using 10-mm and even 5-mm sl
ices.