In a 6-year-old woman, symptomatic headache caused by a mucocele of th
e sphenoid sinus led to ergotamine abuse and subsequent ergotamine-ind
uced headache. Since there were no neurological symptoms initially and
the patient previously suffered from migraine, the mucocele was not r
ecognized. Only after unsuccessful drug withdrawal therapy and an MRI,
was the correct diagnosis made. Surgical removal of the mucocele led
to complete relief of headache within 3 weeks. We conclude that ergota
mine-induced headache can develop on the basis of symptomatic headache
. In spite of the effectiveness of ergotamine tartrate, an MRI should
be performed if focal neurological symptoms occur.