We have investigated the suppression of single-electron charging effec
ts in metallic single-electron transistors when the conductance of the
tunnel junctions becomes larger than the conductance quantum e(2)/h.
We find that the Coulomb blockade of the conductance is progressively
shifted at lower temperatures. The experimental results agree quantita
tively with the available 1/T expansion at high temperature, and quali
tatively with the predictions of an effective two-state model at low t
emperature, which predicts at T = 0 a blockade of conductance for all
gate voltages.