MESO-IONIC 4-BENZYL-2-PHENYL-1,3-OXAZOLIUM-5-OLATE BY-PRODUCT FOUND IN CARBODIIMIDE-MEDIATED PEPTIDE-SYNTHESIS

Authors
SLEBIODA M
Citation
M. Slebioda, MESO-IONIC 4-BENZYL-2-PHENYL-1,3-OXAZOLIUM-5-OLATE BY-PRODUCT FOUND IN CARBODIIMIDE-MEDIATED PEPTIDE-SYNTHESIS, Polish Journal of Chemistry, 71(8), 1997, pp. 1045-1048
Citations number
6
Categorie Soggetti
Chemistry
Journal title
Polish Journal of Chemistry → ACNP
ISSN journal
01375083
Volume
71
Issue
8
Year of publication
1997
Pages
1045 - 1048
Database
ISI
SICI code
0137-5083(1997)71:8<1045:M4BFI>2.0.ZU;2-A
Abstract
Formation of 4-benzyl-2-phenyl-1,3-oxazolium-5-olate was observed duri ng carbodiimide-mediated N-benzoyl-phenylalanyl-leucine methyl ester s ynthesis. This mesoionic compound can also be obtained by tautomeric t ransformation of 4-benzyl-2-phenyl-5(4H)-oxazolone in yield (3% to 60% ) depending on the type of solvent and tertiary amine catalyst used.