BRAIN-DERIVED NEUROTROPHIC FACTOR IN HUMAN PLATELETS

Authors
PLIEGORIVERO FB BAYATTI N GIANNAKOULOPOULOS X GLOVER V BRADFORD HF STERN G SANDLER M
Citation
Fb. Pliegorivero et al., BRAIN-DERIVED NEUROTROPHIC FACTOR IN HUMAN PLATELETS, Biochemical pharmacology, 54(1), 1997, pp. 207-209
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Biology
Journal title
Biochemical pharmacology → ACNP
ISSN journal
00062952
Volume
54
Issue
1
Year of publication
1997
Pages
207 - 209
Database
ISI
SICI code
0006-2952(1997)54:1<207:BNFIHP>2.0.ZU;2-K
Abstract
A sensitive, capture enzyme-linked immunosorbent assay (CELISA) has be en applied to the accurate and reproducible measurement of brain-deriv ed neurotrophic factor (BDNF) protein in normal human blood platelets, a mean concentration of 1.03 +/- 0.04 ng (SEM)/mg of platelet protein being observed. The method, which requires only 10 ml brood, is now s uitable for the investigation of a variety of clinical disorders. (C) 1997 Elsevier Science Inc.