OVERCOMING STREPTOCOCCUS-AGALACTIAE IN-VITRO RESISTANCE TO IMIDAZOLES

The increased diffusion of Streptococcus agalactiae in the urinary tra ct and vagina has affected the strain's resistance to antimicrobial ag ents, so we decided to study the possibility of overcoming its resista nce to imidazoles. Our data suggest that overcoming S. agalactiae resi stance to imidazoles in contact and growth culture tests depends partl y on the electrical conductivity of the culture medium. Although imida zole contact activity and culture activity have different targets in c ell structures, we have demonstrated that imidazole resistance in S. a galactiae tine cells in both types of tests can be affected by the sam e conditions regulating membrane permeability.