Through the introduction of newly invented high-performance gradient s
ystems to MRI, which enable for echoplanar imaging (EPI), also magneti
c resonance angiography (MRA) has gained an entirely new field of appl
ications and techniques. Ultrafast imaging techniques in MRA allow the
investigation of larger Vascular areas within a single breath-hold-pe
riod. Artifacts like motion induced signal misregistrations, dephasing
or saturation of the vascular signal are minimized by extremely short
echo times. The technique thus requires the intravenous application o
f a contrast media bolus, usually a gadolinium compound, which is in s
tandard clinical use. Coordination of the bolus injection and the timi
ng of the data acquisition is crucial for optimal results. The first p
ass evaluation of the contrast media resembles CTA to a certain extend
. Due to the fast measurement and the high contrast in contrast-enhanc
ed MRA (CE-MRA) new applications and indications are developed like MR
A of the pulmonary vessels. The paper offers considerations and trials
for optimization of thoracical CE-MRA. Besides parameter constellatio
n also bolus-optimization is described with respect to the dedicated a
natomical premises. investigations on volunteers and on patients build
a basis for suggestions on optimized CE-MRA procedures. To date, a fi
nal estimation of the clinical value of the new technique cannot be gi
ven since ongoing improvements change the optimal protocol frequently
and the potential of further developments is high.