D. Laurain et al., PRODUCTION OF GINKGOLIDE AND BILOBALIDE IN TRANSFORMED AND GAMETOPHYTE DERIVED CELL-CULTURES OF GINKGO-BILOBA, Phytochemistry, 46(1), 1997, pp. 127-130
Ginkgolide and bilobalide were detected by HPLC analysis in cell cultu
res established from various G. biloba explants. These secondary metab
olites of pharmacological interest were found to occur in concentratio
ns of 0.065 and 0.087% (dry weight) in two cell suspensions. One was d
erived from a female prothallus and the other one from putatively tran
sformed embryos, by transfection via Agrobacterium rhizogenes agropine
type strain CFBP 2409 (A4). (C) 1997 Elsevier Science Ltd. All rights
reserved.