SYNTHESIS OF 1H-2-PYRIDYLPYRROLES AND 1-VINYL-2-PYRIDYLPYRROLES BY THE TROFIMOV REACTION

Authors
PETROVA OV MIKHALEVA AI SOBENINA LN SCHMIDT EY KOSITSYNA EI
Citation
Ov. Petrova et al., SYNTHESIS OF 1H-2-PYRIDYLPYRROLES AND 1-VINYL-2-PYRIDYLPYRROLES BY THE TROFIMOV REACTION, Mendeleev communications, (4), 1997, pp. 162-163
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Mendeleev communications → ACNP
ISSN journal
09599436
Issue
4
Year of publication
1997
Pages
162 - 163
Database
ISI
SICI code
0959-9436(1997):4<162:SO1A1B>2.0.ZU;2-8
Abstract
A one-pot synthesis of 2-(2-pyridyl)-1H-pyrrole and 1-vinyl-2-(3-pyrid yl)-, 1-vinyl-2-(4-pyridyl)-and 1-vinyl-2-(4-pyridyl)-pyrroles from ox imes of 2-acetyl-, 3-acetyl- and 4-acetylpyridine and acetylene under pressure (16-25 arm) in a KOH/DMSO system has been carried out (105-12 0 degrees C, 3 h) to reveal for the first time the applicability of th e Trofimov reaction for the preparation of alkaloids of the nicotine s eries.