NEW EFFICIENT SYNTHESES OF ALPHA-DIFLUOROMETHYL-ORNITHINE AND ALPHA-TRIFLUOROMETHYL-ORNITHINE

Authors
OSIPOV SN GOLUBEV AS SEWALD N BURGER K
Citation
Sn. Osipov et al., NEW EFFICIENT SYNTHESES OF ALPHA-DIFLUOROMETHYL-ORNITHINE AND ALPHA-TRIFLUOROMETHYL-ORNITHINE, Tetrahedron letters, 38(34), 1997, pp. 5965-5966
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
34
Year of publication
1997
Pages
5965 - 5966
Database
ISI
SICI code
0040-4039(1997)38:34<5965:NESOAA>2.0.ZU;2-K
Abstract
A new efficient method far the preparation of ornithine derivatives 3- 5 is described. The key step of the synthesis is the regioselective al kylation of imine 2 with propargyl amine 1. (C) 1997 Elsevier Science Ltd.