PAROXETINE AND GALACTORRHEA

The authors report a case of galactorrhea following antidepressant tre atment where paroxetine might be responsible. Paroxetine is a selectiv e serotonergic reuptake inhibitor (SSRI). Galactorrhea occasionally is a dopamine-mediated side effect observed with neuroleptic drugs. Howe ver, the ability to produce extrapyramidal side effects is known for t ricyclic as well as for SSRIs. Thus the potential of SSRIs to induce d opamine-dependent side effects is a clinical reality and it was not su rprising to observe galactorrhea due to paroxetine. However, in a revi ew of the literature no reported cases of galactorrhea associated with paroxetine were found.