A MUTASE MIMIC WITH COBALAMIN LINKED TO CYCLODEXTRIN

Authors
Citation
M. Rezac et R. Breslow, A MUTASE MIMIC WITH COBALAMIN LINKED TO CYCLODEXTRIN, Tetrahedron letters, 38(33), 1997, pp. 5763-5766
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
38
Issue
33
Year of publication
1997
Pages
5763 - 5766
Database
ISI
SICI code
0040-4039(1997)38:33<5763:AMMWCL>2.0.ZU;2-0
Abstract
Cobalamin covalently tethered to beta-cyclodextrin was synthesized as a methylmalonyl-CoA mutase mimic. The artificial enzyme is capable of discriminating between two substrates containing different binding gro ups. (C) 1997 Elsevier Science Ltd.