2,4-DINITROBENZENESULFONAMIDES - A SIMPLE AND PRACTICAL METHOD FOR THE PREPARATION OF A VARIETY OF SECONDARY-AMINES AND DIAMINES

2,4-Dinitrobenzenesulfonamides, readily prepared from primary amines a nd 2,4-dinitrobenzenesulfonyl chloride,can be alkylated by the Mitsuno bu reaction or by the conventional methods to give N,N-disubstituted s ulfonamides in excellent yields Since 2,4-dinitrobenzenesulfonamides c an be removed without deprotecting 2-nitrobenzenesulfonamides, a wide variety of diamines could be prepared by the combined use of these pro tecting/activating groups. (C) 1997 Elsevier Science Ltd.