CALIX[4]ARENE BASED ALPHA-AMINOPHOSPHONATES - NOVEL CARRIERS FOR ZWITTERIONIC AMINO-ACIDS TRANSPORT

Authors
ANTIPIN IS STOIKOV II PINKHASSIK EM FITSEVA NA STIBOR I KONOVALOV AI
Citation
Is. Antipin et al., CALIX[4]ARENE BASED ALPHA-AMINOPHOSPHONATES - NOVEL CARRIERS FOR ZWITTERIONIC AMINO-ACIDS TRANSPORT, Tetrahedron letters, 38(33), 1997, pp. 5865-5868
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
33
Year of publication
1997
Pages
5865 - 5868
Database
ISI
SICI code
0040-4039(1997)38:33<5865:CBA-NC>2.0.ZU;2-7
Abstract
A series of calix[4]arene based alpha-aminophosphonates were synthesiz ed by the Kabachnik-Fields reaction of the calixarene-diamine (either at lower or upper rim), diethyl phosphite and a carbonyl compound (ace tone or cyclohexanone). These compounds exhibited remarkable selectivi ty as carriers for the membrane transport of the zwitterionic form of aromatic amino acids. (C) 1997 Elsevier Science Ltd.