A. Giovannini et al., CHOROIDAL FINDINGS IN THE COURSE OF IDIOPATHIC SEROUS PIGMENT-EPITHELIUM DETACHMENT DETECTED BY INDOCYANINE GREEN VIDEOANGIOGRAPHY, Retina, 17(4), 1997, pp. 286-293
Purpose: To analyze the choroidal alterations associated with idiopath
ic serous pigment epithelium detachment. Methods: Twenty-five consecut
ive patients affected by idiopathic serous pigment epithelium detachme
nt underwent ophthalmoscopy, fluorescein angiography, and indocyanine
green videoangiography. Results: On indocyanine green videoangiography
an early, complete, and homogeneous filling of the pigment epithelium
detachment was always observed. In the late phases, the indocyanine g
reen pattern depended on the size of the detachment. An idiopathic ser
ous pigment epithelium detachment larger than the diameter of one opti
c disk was still hyperfluorescent in the late phases of indocyanine gr
een videoangiography and was surrounded by a ring of brighter hyperflu
orescence. An idiopathic serous pigment epithelium detachment smaller
than the diameter of one optic disk usually could be visualized in the
late phases as a hypofluorescent area surrounded by a hyperfluorescen
t ring. In 30 eyes (83.3%), choroidal hyperpermeability was observed,
An irregular dilatation of the choroidal veins at the site or within a
n area the size of one disk diameter from the detachments could be vis
ualized on indocyanine green videoangiography in 12 of 36 affected eye
s (33.3%); in three cases an active focus of central serous chorioreti
nopathy with subretinal leakage developed in the follow-up period,Conc
lusion: The observation that pigment epithelium detachments frequently
are associated with choroidal leakage and venous dilatation supports
the hypothesis that an idiopathic serous pigment epithelium detachment
is a variant of central serous chorioretinopathy. Moreover, the choro
idal permeability alterations detected by indocyanine green videoangio
graphy would support the theory of Gass that idiopathic serous pigment
epithelium detachments could be caused by exudation of fluids from th
e choroidal vessels.