Background: Silicone keratopathy frequently develops as a complication
of silicone oil tamponade in the management of severe trauma in eyes
with partial or complete aniridia, We therefore designed an ''open'' a
rtificial iris diaphragm to prevent silicone oil-endothelial contact.
In hypotony, where insufficient circulation of aqueous allows silicone
in the anterior chamber despite an open diaphragm, a new solution bec
ame necessary. The ''closed'' artificial diaphragm was developed. Meth
ods: In this retrospective study, two consecutive series of artificial
iris diaphragms were compared. Forty-four patients received either an
open type (20 eyes) or a closed type (24 eyes) and were observed for
409 +/- 421 days (range, 32-1912). All eyes were aphakic, normotonous,
and had a traumatic, compromised iris diaphragm or were aphakic and h
ypotonic as a result of injury, proliferative vitreoretinopathy, proli
ferative diabetic retinopathy, or uveitis, with an intact natural iris
diaphragm. Results: Silicone oil was retained behind the open diaphra
gm throughout the observation period in 40% of the eyes. Major long-te
rm complications were hypotony and fibrous overgrowth. Silicone was re
tained behind the closed diaphragm in 50% of the eyes. Conclusion: Bec
ause proliferative vitreoretinopathy is active for months and multiple
surgical interventions become necessary to avoid phthisis in eyes wit
h highly pathologic changes, longstanding or permanent silicone tampon
ade is used, The artificial diaphragm prevents silicone-corneal contac
t in approximately 50% of aphakic eyes for at least 1 year.