INACTIVATION OF CHEMOTACTIC PEPTIDES BY AMINOPEPTIDASE EY FROM HENS (GALLUS-GALLUS-DOMESTICUS) EGG-YOLK

Authors
TANAKA T ICHISHIMA E
Citation
T. Tanaka et E. Ichishima, INACTIVATION OF CHEMOTACTIC PEPTIDES BY AMINOPEPTIDASE EY FROM HENS (GALLUS-GALLUS-DOMESTICUS) EGG-YOLK, Comparative biochemistry and physiology. B. Comparative biochemistry, 107(4), 1994, pp. 533-538
Citations number
30
Categorie Soggetti
Biology
Journal title
Comparative biochemistry and physiology. B. Comparative biochemistry → ACNP
ISSN journal
03050491
Volume
107
Issue
4
Year of publication
1994
Pages
533 - 538
Database
ISI
SICI code
0305-0491(1994)107:4<533:IOCPBA>2.0.ZU;2-4
Abstract
Aminopeptidase Ey, purified from hen's (Gallus gallus domesticus) egg yolk, was studied for its specificity against N-blocked peptides. Only N-formyhnethionyl peptides were hydrolyzed by the enzyme in the teste d peptides. N-Formyl-methionyl-leucyl-phenylalanine (fMet-Leu-Phe) los t its chemotactic activity toward human neutrophil after incubation wi th aminopeptidase Ey.