A RANDOMIZED CONTROLLED SINGLE-BLIND STUDY OF THE EFFICACY OF CLONAZEPAM AND LITHIUM IN THE TREATMENT OF ACUTE MANIA

Authors
CLARK HM BERK M BROOK S
Citation
Hm. Clark et al., A RANDOMIZED CONTROLLED SINGLE-BLIND STUDY OF THE EFFICACY OF CLONAZEPAM AND LITHIUM IN THE TREATMENT OF ACUTE MANIA, Human psychopharmacology, 12(4), 1997, pp. 325-328
Citations number
17
Categorie Soggetti
Psychology,"Pharmacology & Pharmacy","Clinical Neurology
Journal title
Human psychopharmacology → ACNP
ISSN journal
08856222
Volume
12
Issue
4
Year of publication
1997
Pages
325 - 328
Database
ISI
SICI code
0885-6222(1997)12:4<325:ARCSSO>2.0.ZU;2-T
Abstract
This study is a randomized controlled trial of 40 patients suffering f rom bipolar affective disorder, manic phase (DSM IV). The patients wer e treated with either clonazepam or lithium. There were-no differences between the two groups at 4 weeks on any of the efficacy measures, wh ich included the BPRS, MAS, CGI and GAF scales. Side-effects were comp arably mild in both groups. Clonazepam may be an effective treatment f or acute mania. (C) 1997 John Wiley & Sons, Ltd.