T. Demant et Cj. Packard, STUDIES OF APOLIPOPROTEIN B-100 METABOLISM USING RADIOTRACERS AND STABLE ISOTOPES, European journal of pediatrics, 156, 1997, pp. 75-77
Apolipoprotein B metabolism can be investigated in-vivo either by exog
enous radiolabeling of preformed lipoproteins or by endogenous labelli
ng of denovo synthesized apo B using a stable isotope substituted amin
o acid tracer. The potential of both methods and results obtained by i
n-vivo studies in genetically determined dys- or hyperlipidaemic subje
cts will be discussed.