NOVEL RING TRANSFORMATION OF NITROPYRIMIDINONE - SYNTHETIC EQUIVALENTOF ALPHA-NITROFORMYLACETIC ACID

Authors
NISHIWAKI N WANG HP MATSUO K TOHDA Y ARIGA M
Citation
N. Nishiwaki et al., NOVEL RING TRANSFORMATION OF NITROPYRIMIDINONE - SYNTHETIC EQUIVALENTOF ALPHA-NITROFORMYLACETIC ACID, Journal of the Chemical Society. Perkin transactions. I, (16), 1997, pp. 2261-2262
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
16
Year of publication
1997
Pages
2261 - 2262
Database
ISI
SICI code
0300-922X(1997):16<2261:NRTON->2.0.ZU;2-R
Abstract
3-Methyl-5-nitropyrimidin-4(3H)-one reacts with ketones in the presenc e of ammonium salts to afford disubstituted pyrimidines and disubstitu ted 3-nitro-2-pyridones in a novel ring transformation reaction; nitro pyrimidinone behaves as an activated diformylamine in the former case, and as a synthetic equivalent of alpha-nitroformylacetic acid in the latter case.