A REGIOSELECTIVE AND STEREOSELECTIVE INTRODUCTION OF AZIDE AT C-4 OF 2,3-UNSATURATED N-ACETYLNEURAMINIC ACIDS

Authors
KOK GB VONITZSTEIN M
Citation
Gb. Kok et M. Vonitzstein, A REGIOSELECTIVE AND STEREOSELECTIVE INTRODUCTION OF AZIDE AT C-4 OF 2,3-UNSATURATED N-ACETYLNEURAMINIC ACIDS, Carbohydrate research, 302(3-4), 1997, pp. 237-240
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
302
Issue
3-4
Year of publication
1997
Pages
237 - 240
Database
ISI
SICI code
0008-6215(1997)302:3-4<237:ARASIO>2.0.ZU;2-G
Abstract
The regio-and stereo-selective azidation of the peracetate methyl este rs of 4-epi-Neu5Ac2en and 6-thio-4-epi-Neu5Ac2en has been achieved usi ng Pd(0) chemistry in good yield (> 80%). These 4-epi-azido-4-deoxy-Ne u5Ac2en derivatives provide interesting biological probes. (C) 1997 El sevier Science Ltd.