Plastination is a unique technique of tissue preservation developed by
Dr. Gunther von Hagens in Heidelberg, Germany, in 1978. In this proce
ss, water and lipids in biological tissues are replaced by curable pol
ymers which are subsequently hardened, resulting in dry, odorless and
durable specimens, In neuroanatomy silicone and polyester resins are u
sed. Silicone rubber is used for whole brains and brain dissections re
sulting in natural looking specimens. Polyester resin is used for brai
n slices resulting in an excellent distinction between gray and white
matter. The silicone S 10 standard technique and the polyester P 35 te
chnique are described in detail, The advantages of plastinated specime
ns in neuroanatomy teaching and research are discussed.