The aim of this study was to analyze the composition of dental plaque
according to sucrose exposure. Twelve adult volunteers took part in th
is crossover study done in four phases of 28 days each. For each phase
of the study, an acrylic resin appliance containing four human dental
enamel blocks was constructed for each volunteer. A 20% sucrose solut
ion was dripped onto the enamel blocks from 0 to 8 times/day. The volu
nteers were randomly assigned to the treatments. During the experiment
al period all the subjects used fluoride-free dentifrice, refrained fr
om brushing the enamel blocks and drank water fluoridated at 0.70 ppm
F. After each phase the concentrations of fluoride (F), calcium (Ca),
phosphorus (P) and total carbohydrate were determined in dental plaque
. Statistical analyses showed that frequent sucrose exposure significa
ntly (p<0.05) reduced the F, Ca and P concentrations in dental plaque,
but increased the alkali-soluble carbohydrate concentration. The resu
lts suggest that the cariogenicity of dental plaque formed in the pres
ence of sucrose cannot be attributed only to its higher porosity, but
the lower inorganic concentration may also be important.