Glossopharyngeal neuralgia is a rare disease. In this re port; six cas
es of glossopharyngeal neuralgia have been studied. At first, drug the
rapy was used in all of the 6 cases. In 2 of the 6 cases which were re
sistant to medical therapy intracranial section of the 9th nerve as we
ll as the upper two rootlets of the 10th nerve were performed. This re
solved the symptoms completely. One of these two cases, had, in additi
on to pain paroxyms, hypotension, bradycardia and syncope, which were
controlled by temporary cardiac pacemaker. In the other 4 cases, drug
therapy was able to control the paroxysms of pain. In addition, two pa
tients with weight loss and one patient with bradycardia rapidly respo
nded to drug therapy as well. Reviewing the literature, we discuss the
medical and surgical treatment of glossopharyngeal neuralgia and poss
ible mechanisms of associated cardiovascular disturbances.