An abnormal thyroid echographic pattern, characterized by a diffuse lo
w thyroid echogenicity associated with a reduced thyroid volume, was f
ound in 53 of 55 (96%) patients with atrophic thyroiditis. In 10 of th
ese patients, the ultrasound examination was diagnostic for thyroid at
rophy, whereas the scintiscan had no abnormality. In only two cases wa
s the reverse observed, ie, absent thyroid radioiodine uptake and no e
vidence of abnormality in the ultrasound examination. Six out of 24 (2
5%) patients with thyroperoxidase antibody titers less than or equal t
o 1:1600 and 4 of 31 (13%) patients with titers less than or equal to
1:6400 had a normal thyroid scintiscan in the presence of an abnormal
thyroid echographic pattern. Thus, thyroid echography can be considere
d the first morphological procedure in patients with hypothyroidism du
e to atrophic thyroiditis, and thyroid scintiscan can be used to confi
rm the diagnosis when other results are not definitive. (C) 1994 John
Wiley and Sons, Inc.