H. Tronel et al., LOW-DENSITY-LIPOPROTEIN ABILITY TO GENERATE LIPOPEROXIDES IN HEALTHY-SUBJECTS - VARIATIONS ACCORDING TO AGE, Annals of nutrition & metabolism, 41(3), 1997, pp. 160-165
Oxidized low-density lipoproteins (LDLs) are recognized to be involved
in atherosclerosis development. Since the plasma oxidized LDL assay i
s inadequate because of the short half-lives of LDLs, measurement of t
he in vitro ability of LDLs to generate lipoperoxides (LDL GLs) has be
en preferred. The present study displays a profile of LDL-GLs in a gro
up of 175 healthy subjects, using a method to measure thiobarbituric a
cid-reactive substances. We have observed an increased LDL GL level ac
cording to age.