DETECTION OF 14-3-3-PROTEIN IN THE CSF OF GENETIC CREUTZFELDT-JAKOB-DISEASE

Authors
ROSENMANN H MEINER Z KAHANA E HALIMI M LENETSKY E ABRAMSKY O GABIZON R
Citation
H. Rosenmann et al., DETECTION OF 14-3-3-PROTEIN IN THE CSF OF GENETIC CREUTZFELDT-JAKOB-DISEASE, Neurology, 49(2), 1997, pp. 593-595
Citations number
10
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
49
Issue
2
Year of publication
1997
Pages
593 - 595
Database
ISI
SICI code
0028-3878(1997)49:2<593:DO1ITC>2.0.ZU;2-5
Abstract
The 14-3-3 protein, a protein involved in signal transduction, is pres ent in the CSF of patients with Creutzfeldt-Jakob disease (CJD) and no t in patients with other dementing diseases. We show here that this is also true for patients with E200K CJD, but not for healthy carriers o f the mutation.