The effect of exposure to inorganic mercury on the pregnant woman and
her foetus has received little attention. Transport of elemental inorg
anic mercury into foetal tissues has been reported, and prior studies
indicate a higher incidence of adverse pregnancy outcome. The effects
oi occupational exposure to inorganic mercury on pregnancy were invest
igated among 46 exposed women workers; controls were 19 women working
in non-production areas of the same factory. There were 104 recorded t
otal pregnancies during the period 1948-77. The study revealed a highe
r frequency oi adverse reproductive outcomes, especially congenital an
omalies, among the women exposed to inorganic mercury levels at or sub
stantially lower than 0.6 mg/m(3); no significant differences in the s
tillbirth or miscarriage rates were noted between the two groups of wo
men. The overall foetal death rate in this study was similar to New Yo
rk state (USA) and national levels for the same period.