In this article the state-of-the-art of Open Tubular Liquid Chromatogr
aphy (OTLC) is discussed. In OTLC separations are performed in capilla
ries with an internal diameter of 5 to 10 mu m. Attention is given to
the progress in the preparation of thick stationary phases in these ca
pillaries and to detection. Various efficient separations on OTLC colu
mns are shown.