TRANSVAGINAL INTERSTITIAL LASER TREATMENT OF THE OVARY FOR THE MANAGEMENT OF CHRONIC HYPERANDROGENIC ANOVULATION - FIRST CLINICAL-EXPERIENCE

The feasibility of ultrasound-guided transvaginal interstitial laser t reatment of the ovary (TILT) and its efficacy for ovulation induction was investigated in 3 hormone-therapy-resistant patients with chronic hyperandrogenic anovulation. TILT was performed at powers of 1-2 W and exposures of 75-600 s. Clear-cut hyperechogenic zones developed durin g laser irradiation with diameters of up to 13.7 mm. Spontaneous ovula tion and/or hormonal changes after TILT did not occur. No adhesion for mation was seen during a laparoscopy or laparotomy in 2 patients 6 mon ths after TILT. In conclusion, TILT of the ovaries was simple to perfo rm but so far the clinical results are disappointing. Further studies with a modified technique are necessary to further investigate the eff icacy of TILT.