LOCALIZATION OF A 25 KDA HUMAN SPERM SURFACE PROTEIN - ITS ROLE IN IN-VITRO HUMAN SPERM CAPACITATION

Authors
BANERJEE M CHOWDHURY M
Citation
M. Banerjee et M. Chowdhury, LOCALIZATION OF A 25 KDA HUMAN SPERM SURFACE PROTEIN - ITS ROLE IN IN-VITRO HUMAN SPERM CAPACITATION, Molecular human reproduction, 3(2), 1997, pp. 109-114
Citations number
30
Categorie Soggetti
Reproductive Biology","Developmental Biology
Journal title
Molecular human reproduction → ACNP
ISSN journal
13609947
Volume
3
Issue
2
Year of publication
1997
Pages
109 - 114
Database
ISI
SICI code
1360-9947(1997)3:2<109:LOA2KH>2.0.ZU;2-0
Abstract
A human endometrial sialic acid-binding glycoprotein (SABP) binds spec ifically to a 25 kDa protein on the plasma membranes of human non-capa citated sperm heads. In-vitro labelling of the sperm surface sialoglyc oconjugates and subsequent incubation with SABP, suggests removal of s ome sialoglycoconjugate moieties from the sperm surface upon interacti on with SABP. SABP also induces the exposure of mannose ligand recepto rs on the sperm surface and increases the production of superoxide ani on (O-2(.-)).