SYNTHESIS AND STEREOCHEMISTRY OF SOME NEW DERIVATIVES OF 1,5-DIOXASPIRO[5.5]UNDECANE

Authors
GROSU I PLE G MESAROS C MAGER S
Citation
I. Grosu et al., SYNTHESIS AND STEREOCHEMISTRY OF SOME NEW DERIVATIVES OF 1,5-DIOXASPIRO[5.5]UNDECANE, Heterocyclic communications, 3(4), 1997, pp. 345-354
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocyclic communications → ACNP
ISSN journal
07930283
Volume
3
Issue
4
Year of publication
1997
Pages
345 - 354
Database
ISI
SICI code
0793-0283(1997)3:4<345:SASOSN>2.0.ZU;2-C
Abstract
The stereoisomerism of some spiro-1,3-dioxanes obtained from substitut ed cyclohexanones and 2-methyl-2-ethyl-1,3-propanediol is discussed on the basis of the helical chirality of the 1,5-dioxaspiro[5.5]undecane skeleton and of the data of conformational analysis. The influence of the flexibility of the rings on the representative number of isomers and on their NMR spectra is commented. The isomers (diastereomers and enantiomers) of some peculiar compounds were separated by gas chromato graphy using chiral columns.