Ka. Greene et al., ACUTE AXIS FRACTURES - ANALYSIS OF MANAGEMENT AND OUTCOME IN 340 CONSECUTIVE CASES, Spine (Philadelphia, Pa. 1976), 22(16), 1997, pp. 1843-1852
Study Design. Retrospective review of acute axis fractures treated at
a tertiary referral center. Objective. To determine the optimal treatm
ent of axis fractures based on 340 cases from a single institution. Su
mmary of Background Data. Axis fractures account for almost 20% of acu
te cervical spine fractures. However, their management and the clinica
l criteria predictive of nonoperative failure remain unclear. Methods.
Admission imaging studies and clinical variables were obtained for 34
0 consecutive axis fracture patients. Fractures were classified as odo
ntoid Type I, II, or III with dens displacement on admission roentgeno
grams; hangman's fractures of Francis grade and Effendi type; and misc
ellaneous fractures. Treatment methods were documented, and outcomes w
ere based on dynamic lateral roentgenograms, clinical examination, or
telephone interviews at last follow-up. Results. Follow-up data were a
vailable in 92% of cases. Type II odontoid fractures comprised 35% of
all axis fractures, were the most difficult to treat, and had the high
est nonunion rate (28.4%). Odontoid displacement of 6 mm or more was a
ssociated with Type II nonunion (chi-square = 33.74, P < 0.0001). Pati
ents underwent surgical fusion if fracture alignment could not be main
tained by an external orthosis, or if they had odontoid fractures with
transverse ligament disruption, Type II odontoid fractures with dens
displacement of at least 6 mm, or hangman's fractures of severe Franci
s grade or Effendi type. Conclusions. Type II odontoid fractures have
the highest nonunion rate and were associated with dens displacement o
f 6 mm or greater. Early surgical fusion is recommended for acute frac
ture instability despite external immobilization, transverse ligament
disruption, Type II odontoid fractures with dens displacement of at le
ast 6 mm on admission, or severe Francis grade or Effendi-type hangman
's fractures. Otherwise, nonoperative management is sufficient.