Lh. Chou et Rq. Knight, IDIOPATHIC AVASCULAR NECROSIS OF A VERTEBRAL BODY - CASE-REPORT AND LITERATURE-REVIEW, Spine (Philadelphia, Pa. 1976), 22(16), 1997, pp. 1928-1932
Study Design. Case report and literature review. Objectives. To review
the English literature pertaining to idiopathic avascular necrosis of
a vertebral body. As an illustrative example, the case of a 60-year-o
ld woman with idiopathic avascular necrosis of L4 is presented. Summar
y of Background Data. Avascular necrosis of a vertebral body is an unc
ommon entity. Avascular necrosis has been described in the context of
other underlying lesions, such as with malignancy, infection, radiatio
n therapy, and systemic steroid treatment. The intravertebral vacuum c
left phenomenon seen on plain films has been strongly associated with
vertebral body avascular necrosis.Methods. Literature and chart review
was carried out. Vertebral body avascular necrosis was initially iden
tified with imaging studies and confirmed with biopsy. A comprehensive
preoperative evaluation did not identify a specific cause of avascula
r necrosis. The patient underwent vertebral body resection with fibula
allograft struts. Conclusions. Although vertebral body collapse in an
osteoporotic individual is relatively common, a case is reported of v
ertebral body collapse and subsequent necrosis without evidence of und
erlying disease at 48-month follow-up. The current findings support th
e diagnosis of idiopathic avascular necrosis of L4.