Laparoscopic highly selective (anterior and posterior) vagotomy was pe
rformed in 11 patients for duodenal ulcer (n = 10) and duodenal ulcer
with prepyloric ulcer (n = 1), All patients were endoscoped both pre-a
nd postoperatively, There were no perioperative complications, The ave
rage operating time was 3.2 +/- 0.4 hours and the average hospital sta
y was 1.7 +/- 0.2 day (range 1 to 3 days), None of the patients requir
ed parenteral narcotics postoperatively. The patients have been follow
ed for 6 months to 5 years after operation, Ail ulcers healed as demon
strated by endoscopy, There was one recurrence at 9 months in a patien
t who had a prepyloric nicer preoperatively, The recurrence was treate
d successfully with medication, There has been no other long-term morb
idity, Laparoscopic highly selective vagotomy is feasible, safe, requi
res a brief hospital stay, and produces short-term results comparable
with open surgery.