SUDDEN-DEATH DUE TO AUTOIMMUNE ADDISONS-DISEASE IN A 12-YEAR-OLD GIRL

Authors
ALSABRI AM SMITH N BUSUTTIL A
Citation
Am. Alsabri et al., SUDDEN-DEATH DUE TO AUTOIMMUNE ADDISONS-DISEASE IN A 12-YEAR-OLD GIRL, International journal of legal medicine, 110(5), 1997, pp. 278-280
Citations number
26
Categorie Soggetti
Pathology
Journal title
International journal of legal medicine → ACNP
ISSN journal
09379827
Volume
110
Issue
5
Year of publication
1997
Pages
278 - 280
Database
ISI
SICI code
0937-9827(1997)110:5<278:SDTAAI>2.0.ZU;2-6
Abstract
A 12-year-old female suffering from adrenocortical insufficiency showe d symptoms similar to a gastro-enteritis, and severe electrolytic and acid/base disturbances which progressed into cerebral oedema and death . Autopsy findings included depletion of the adrenal cortex, with enla rgement and eosinophilia of surviving cells. In ante-mortem blood, ant i-adrenal auto-antibodies were found and elevated levels of ACTH and c ortisol with a low level of aldosterone.