A NEW ALLELE AT THE SHORT TANDEM REPEAT LOCUS HUMF13A01

Citation
B. Glock et al., A NEW ALLELE AT THE SHORT TANDEM REPEAT LOCUS HUMF13A01, International journal of legal medicine, 110(5), 1997, pp. 284-285
Citations number
12
Categorie Soggetti
Pathology
ISSN journal
09379827
Volume
110
Issue
5
Year of publication
1997
Pages
284 - 285
Database
ISI
SICI code
0937-9827(1997)110:5<284:ANAATS>2.0.ZU;2-2
Abstract
We investigated the (AAAG)n short tandem repeat (STR) polymorphism Hum F13A01 an Austrian Caucasoid population sample (n = 674). PCR amplifie d fragments were detected on an automatic A.L.F. DNA sequencer using l aser-induced fluorescence. A total of 14 alleles could be identified, including a new 179 bp allele which was designated allele 3. Sequence determination of allele 3 confirmed the typing results by revealing th ree continuous copies of the core repeat, whereas in sequencing of 54 additional alleles no further variants or microheterogeneities could b e observed. The population data showed no significant deviation from H ardy-Weinberg equilibrium.