N. Anders et J. Wollensak, INADVERTENT USE OF CHLORHEXIDINE INSTEAD OF BALANCED SALT SOLUTION FOR INTRAOCULAR IRRIGATION, Journal of cataract and refractive surgery, 23(6), 1997, pp. 959-962
In three consecutive cataract operations, chlorhexidine was inadverten
tly used as an intraocular irrigating solution as a result of inattent
iveness of an assistant. In two of the three patients, corneal endothe
lium damage was so severe that penetrating keratoplasty had to be perf
ormed. Further effects included pronounced iris atrophy, anterior cham
ber applanation, and a retrocorneal membrane. In one case, an increase
in intraocular pressure developed. No effects were observed in the re
tina or optic nerve. Inadvertently using chlorhexidine for intraocular
irrigation has far-reaching consequences for the affected eye and is
recognizable by streak formation in the anterior chamber when intraocu
lar infusion is initiated. To avoid such mistakes, the markings of the
two bottles should be of different colors.