P. Abel et al., ERYTHROCYTE CARBONIC-ANHYDRASE ACTIVITY IN SMOKERS AND IN DIABETIC-PATIENTS, EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 105, 1997, pp. 17-19
Carbonic anhydrase activity was measured in lyzed erythrocytes from sm
oking and non-smoking young men as well as from diabetic and healthy y
oung women. Enzyme activity was determined by a changing-pH-assay, usi
ng a stirred reaction vessel and glass pH electrode. CAA was lower in
smokers than in non-smokers. Furthermore, it was lower in diabetics th
an in nondiabetic controls. We conclude that cigarette smoking as well
as diabetes mellitus may reduce erythrocyte carbonic anhydrase activi
ty.