Against the background of an increasing number of patients waiting for
heart transplantation but a stagnating number of transplant procedure
s, long-term mechanical circulatory support is gaining major importanc
e. We investigated the outcome of 20 patients (15 men, and 5 women, ag
ed between 15 and 66 years) each supported for more than 100 days betw
een September 1987 and August 1996. The indications for implantation w
ere bridging in 17 patients, myocarditis in 2 patients, and postcardio
tomy cardiogenic shock in one patient. 12 patients received the Novaco
r LVAD, 4 patients the Thoratec system, 3 patients the HeartMate devic
e and one patient both Novacor and Thoratec. Mean duration of support
was 178.1 days. 15 patients were transplanted, 14 of them could be dis
charged. 2 patients died, 4 patients are still waiting. The most frequ
ent complication was device-related infection in 11 patients. The resu
lts have shown that all three systems are safe and reliable devices fo
r supporting patients for more than 100 days.