Y. Kaneko et al., FIBROUS TISSUE OVERGROWTH AND PROSTHETIC VALVE ENDOCARDITIS - REPORT OF A CASE, The thoracic and cardiovascular surgeon, 45(3), 1997, pp. 150-152
Mechanical valve stenosis without restricted occluder motion and parav
aluvular leakage developed in a patient who had undergone patch closur
e of partial atrioventricular septal defect and replacement of the lef
t atrioventricular valve 13 years previously. Dense calcification of t
he supravalvular region was shown in a cineradiogram, whereas transtho
racic and transesophageal echocardiography failed to reveal any obstru
ctive mechanism. Elevated transprosthetic pressure gradient with unres
tricted occluder motion suggested prosthetic valve stenosis resulting
from fibrous tissue overgrowth, although this was not visualized by th
e modern diagnostic imaging tools. Reoperation confirmed calcified fib
rous tissue overgrowth obstructing the mechanical valve inflow. Examin
ation of resected tissue revealed prosthetic valve endocarditis due to
ct-streptococcus, Paravalvular leakage accompanying fibrous tissue ov
ergrowth may indicate the presence of prosthetic valve infection even
if the clinical manifestations are scarce.