STAGE-IV MALIGNANT INTRAPERICARDIAL GERM-CELL TUMOR - A CASE-REPORT

Authors
BATH LE WALAYAT M MANKAD P GODMAN MJ WALLACE WHB
Citation
Le. Bath et al., STAGE-IV MALIGNANT INTRAPERICARDIAL GERM-CELL TUMOR - A CASE-REPORT, Pediatric hematology and oncology, 14(5), 1997, pp. 451-455
Citations number
10
Categorie Soggetti
Pediatrics,Oncology,Hematology
Journal title
Pediatric hematology and oncology → ACNP
ISSN journal
08880018
Volume
14
Issue
5
Year of publication
1997
Pages
451 - 455
Database
ISI
SICI code
0888-0018(1997)14:5<451:SMIGT->2.0.ZU;2-I
Abstract
The mediastinum is a common site for germ cell tumors. We describe an unusual case in an 18-month-old girl who presented with respiratory di stress and cardiomegaly. An echocardiogram revealed a large pericardia l effusion and a mass adjacent to the heart. She underwent detailed in vestigation and at open exploration was found to have a wholly intrape ricardial malignant yolk sac tumor. Staging investigations revealed a bony metastasis. The serum marker alpha-fetoprotein was elevated. She was treated with chemotherapy and is in remission 1 year after complet ion of treatment. We review the methods of diagnosis and follow-up of children with these tumors.