Dm. Aronoff et Jp. Callen, NECROSING LIVEDO-RETICULARIS IN A PATIENT WITH RECURRENT PULMONARY HEMORRHAGE, Journal of the American Academy of Dermatology, 37(2), 1997, pp. 300-302
The antiphospholipid antibody (APS) syndrome is characterized by antip
hospholipid antibodies (lupus anticoagulant [LA] or anticardiolipin [a
CL], a recurrent arterial and venous thrombosis, recurrent fetal loss,
and thrombocytopenia. Pulmonary hemorrhage is an unusual complication
. We describe a 32-year-old woman with a history of recurrent pulmonar
y hemorrhage and transient renal dysfunction. Her original diagnosis w
as Goodpasture's syndrome, and she was treated with immunosuppressive
drugs. Necrosing Livedo reticularis of the legs subsequently developed
. The presence of aCL and LA in the patient's serum, the finding of no
ninflammatory microthrombi in the dermal capillaries, and the lack of
laboratory or pathologic features of Goodpasture's syndrome, confirmed
a diagnosis of APS in this patient.