Studies of bacterial meningitis have documented a peak of incidence am
ong persons age 60 and older. The most common bacterial pathogens in t
hese patients differ from those seen in children. Presentation of meni
ngitis in older patients may be atypical; fever is not a consistent fi
nding, and nonspecific symptoms such as confusion are often seen. Nuch
al rigidity is not as sensitive nor as specific as in younger patients
. Definitive diagnosis relies on interpretation of CSF studies. Ampici
llin plus a third-generation cephalosporin should be administered for
community-acquired meningitis until Gram's stain and culture results r
eturn. Cases of S pneumoniae meningitis may require varying strategies
, based upon the degree of penicillin resistance.