N. Perez et al., USE OF DISTORTION-PRODUCT OTOACOUSTIC EMISSIONS FOR AUDITORY EVALUATION IN MENIERES-DISEASE, European archives of oto-rhino-laryngology, 254(7), 1997, pp. 329-342
Otoacoustic emissions are a relatively new tool for assessment of inne
r ear function. We studied 65 patients diagnosed as having Meniere's d
isease. In order to obtain and characterize responses at different fre
quencies we used distortion-product otoacoustic emissions (DPOAE). In
unilateral cases, the difference in response between ears on the disea
sed and healthy sides was evident at all frequencies. In the former th
e result was lower than expected for a group of normally hearing subje
cts, while in the latter it was better than expected according to pure
tone averages. Reduction in amplitude and increment in threshold of t
he DPOAE in the diseased ear was a significant finding and could be co
rrelated to the stage of the disease. In those subjects treated with B
etahistine after 1 year's follow-up, DPOAE testing showed the recovery
of response at low frequencies and a reduction of its threshold at al
l frequencies studied.