MALIGNANT-TUMORS IN FAMILIES OF THYROID-CANCER PATIENTS

Authors
VLAJINAC HD ADANJA BJ ZIVALJEVIC VR JANKOVIC RR DZODIC RR JOVANOVIC DD
Citation
Hd. Vlajinac et al., MALIGNANT-TUMORS IN FAMILIES OF THYROID-CANCER PATIENTS, Acta oncologica, 36(5), 1997, pp. 477-481
Citations number
19
Categorie Soggetti
Oncology
Journal title
Acta oncologica → ACNP
ISSN journal
0284186X
Volume
36
Issue
5
Year of publication
1997
Pages
477 - 481
Database
ISI
SICI code
0284-186X(1997)36:5<477:MIFOTP>2.0.ZU;2-7
Abstract
A case-control study comprised 177 patients with Various types of thyr oid cancer and the same number of hospital controls individually match ed by age, sex and place of residence. Malignant tumors were more freq uent among first and second degree relatives of cases as compared to c ontrols. The odds ratio (95% confidence interval) was 2.43 (1.33-4.44) and 5.33 (1.77-16.01) respectively. The most frequent were cancers of uterus and stomach with odds ratio of 6.00 (1.61-22.36) and 9.00 (1.6 4-49.35). Thyroid cancer was present only in first-degree relatives of two cases and none of controls.