REGIOSELECTIVE HYDROLYSIS OF COCAINE AND A CONVENIENT ACYLATION PROCEDURE BY BENZOYLECGONINE

Authors
MARTINET F HUY CP TOMAS A SCHERRMANN JM GALONS H
Citation
F. Martinet et al., REGIOSELECTIVE HYDROLYSIS OF COCAINE AND A CONVENIENT ACYLATION PROCEDURE BY BENZOYLECGONINE, Synthetic communications, 27(19), 1997, pp. 3485-3490
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
27
Issue
19
Year of publication
1997
Pages
3485 - 3490
Database
ISI
SICI code
0039-7911(1997)27:19<3485:RHOCAA>2.0.ZU;2-D
Abstract
Regioselective hydrolysis of cocaine led, according to the reaction co nditions, either to benzoylecgonine or to ecgonine methyl eater. Acyla tion with benzoylecgonine was readily achieved when benzotriazolyloxyt risdimethylaminophosphonium (BOP) was used as a coupling agent.