A SYNTHETIC HEPARIN HEPARAN SULFATE-LIKE DECASACCHARIDE RELEASES LIPASE ACTIVITY IN-VIVO - CHEMICAL SYNTHESIS AND BIOLOGICAL-ACTIVITY/

Authors
PETITOU M DUCHAUSSOY P BERNAT A HOFFMANN P HERBERT JM
Citation
M. Petitou et al., A SYNTHETIC HEPARIN HEPARAN SULFATE-LIKE DECASACCHARIDE RELEASES LIPASE ACTIVITY IN-VIVO - CHEMICAL SYNTHESIS AND BIOLOGICAL-ACTIVITY/, Bioorganic & medicinal chemistry letters, 7(15), 1997, pp. 2067-2070
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
15
Year of publication
1997
Pages
2067 - 2070
Database
ISI
SICI code
0960-894X(1997)7:15<2067:ASHHSD>2.0.ZU;2-F
Abstract
A decasaccharide mimic of the heparan sulfate fragment reported to hav e high affinity for lipoprotein lipase has been synthesised, and shown to release lipase activity in vivo in the rat. (C) 1997 Elsevier Scie nce Ltd.