A UV RESONANT RAMAN-SPECTROSCOPIC STUDY OF THE INTERACTION OF METALLIC DERIVATIVES OF TETRAKIS(4-N-METHYLPYRIDYL)PORPHINE WITH POLYNUCLEOTIDES

Resonance Raman spectra excited at 257 nm are reported for the complex es of the Nickel, Cobalt and Zinc derivatives of Tetrakis(4-N-methylpy ridyl)porphine with poly(dA.dT)(2), poly(dA).poly(dT), poly(dG.dC)(2) and poly(dG).poly(dC). These spectra are interpreted as evidence of mu ltiple outside binding modes with poly(dA).poly(dT), and of evidence f or an outside binding mode with Poly(dG.dC)(2). Some results obtained for the zinc derivative with poly(dA).poly(dT) suggest a binding mode peculiar to this derivative.