MALIGNANT STROMAL TUMOR CONSISTENT WITH FIBROSARCOMA ARISING FROM MECKELS-DIVERTICULUM - CLINICOPATHOLOGICAL STUDY OF AN INCIDENTALLY DISCOVERED TUMOR AND REVIEW OF THE LITERATURE

Citation
Sm. Calderale et al., MALIGNANT STROMAL TUMOR CONSISTENT WITH FIBROSARCOMA ARISING FROM MECKELS-DIVERTICULUM - CLINICOPATHOLOGICAL STUDY OF AN INCIDENTALLY DISCOVERED TUMOR AND REVIEW OF THE LITERATURE, Tumori, 83(3), 1997, pp. 703-708
Citations number
66
Categorie Soggetti
Oncology
Journal title
TumoriACNP
ISSN journal
03008916
Volume
83
Issue
3
Year of publication
1997
Pages
703 - 708
Database
ISI
SICI code
0300-8916(1997)83:3<703:MSTCWF>2.0.ZU;2-1
Abstract
The authors report a case of a Meckel's diverticulum mesenchymal tumor incidentally discovered in a 69-year-old woman undergoing laparotomy for an ovarian cyst. Histological examination of the tumor revealed a fasciculated proliferation of spindle cells that proved to be immunore active to vimentin only; pleomorphism was mild, necrosis extensive and mitotic count high. Because these features were consistent with those of fibrosarcoma, the tumor was classified in the category of gastroin testinal stromal tumors; more specifically, it was considered malignan t for the presence of spread beyond the primary site in the form of pe ritoneal nodules and for the high mitotic count. We have been able to find only one previously reported case of mesenchymal malignant tumor of Meckel's diverticulum classified as fibrosarcoma among the 199 mali gnant tumors described in the literature. Based on this personal exper ience and on the review of the literature concerning malignant tumors of Meckel's diverticulum, we discuss both the rarity of these tumors a nd the importance of removing Meckel's diverticulum every time it is f ound during laparotomy.